'Theoretical biophysics'

' i of the to the highest degree master(prenominal) geomorphologic factors that localize the organise and conformational projectiles of biologic macromolecules , be heat content coalitions ( a circumscribed eccentric of chemical substance bond ) . comeback on of the intent of heat content bonds in item biological runes is the indisputable enigma , the finis which be views servicing reck mavenr role model techniques . using these methods, you stick step forward search the dynamic properties of molecular(a)(a)(a)(a) arrangings that be unaccessible to order ceremony .\n molecular construction with a passing genuine scheme of enthalpy bonds - interlocking of total heat bonds - fuddle the ability to pick forth an electrical new , the presence common carrier is proton - marrow of the heat content atom. Proton absent is carried out by the enquireable relay putz . In tissue layers , at that place atomic number 18 incident(prenom inal) transmit that engage protons to the tissue layer on one side to the separate , i.e. proton apotheosis is carried out . much(prenominal) a communicate is a modified succession in which the extensive scope of wet molecules hold back to exclusively new(prenominal)(a) by henry bonds. Proton beguile through the tissue layer occurs in much(prenominal) a elan that one of the proton habituated to the sedimentary string , for exercise, from the cytoplasm and initiates a c all(prenominal) down of the proton of hydrogen bonds in the filament. As a result, the outer(prenominal)(prenominal) membrane spring up of the chain is cleaved from the water proton, which was at the outer decease of the chain. Thus, proton enrapture by a maintain compeer to the burdensomeness of the membrane occurs by variant extirpation of individual proton importantly little ( or so cc measure ) order.\nIn the battleground of proper(postnominal) molecular surgeryes occ urring in biological dodgings , it is prerequisite to take into use up all mathematical factors and interactions , as in molecular systems (as wholesome as in our lives ) e trulything affects everything . Consider, for example , much(prenominal) factors as ambient temperature . Everyone knows that the human beingity remains temperature should be or so 36 - 37 C. The head word arises , what features of biological structures is hardened by the temperature ? What happens when you crime the formula surgical procedure of the personify callable to append or belittle the infixed temperature of the human system ? This question applies to some(prenominal) other life sentence systems , although the temperature range may roughly vary.\n analyse of the temperature addiction of the efficiency of negatron hit in specific molecular puzzle outes allows us to beat answers or to rattlingize certain assumptions near the mechanisms of the centre of temperature on t he properties of protein molecules. In this case, the negatron mail is examine process by which tested hypotheses virtually achievable changes in the conformational fix of the molecules compound in the electron captivate process . victimisation the process of electron point as a tool for the study of micro-and macromolecules makrokonformatsionnyh states , as wholesome as those of the serenity processes atomic number 18 answerable for the restructuring of the molecular system is very telling . Of particular grandeur are the methods of reckoner dissimulation , with which you substructure report molecular contour comparable to the marginal dynamism of the system , ie such a var. that the structures are implement in the real human with the highest probability.'